Proton pump inhibitors and gastric neoplasia

Proton Pump Inhibitors and Gastric Acid Secretion

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Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors

Äbelö, A. 2003. Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 303. 47 pp. Uppsala. ISBN 91-554-5806-8. Acid related diseases like GERD, duodenal-and gastric ulcers and H. Pylori-positive peptic ulcer disease are primarily managed by reducing ga...

Gastric corpus polyps associated with Proton Pump Inhibitors therapy.

The prevalence of Gastroesophageal Reflux Disease (GERD) is rapidly rising in Asia. We describe here a case of 51 years old man who had surgery for esophageal leiomyoma and received long-term therapy with Proton Pump Inhibitors (PPIs) for persisting reflux symptoms. On Esophago-Gastroduodenoscopy (EGD) several sessile polyps were seen in the gastric corpus. Earlier EGD done 15 years back had no...

Proton Pump Inhibitors: Omeprazole

Oral Proton Pump Inhibitors

There is currently a lack of evidence to suggest superior clinical efficacy of one oral proton pump inhibitor over any other. Proton pump inhibitors display similar doseresponse relationships with similar potencies and efficacies at the equivalent dose. The decision to select one proton pump inhibitor over another is likely to be based on the agents’ licensed indication, patient tolerability an...